THE INTERACTION OF A SELF-ASSEMBLED NANOPARTICLE AND A LIPID MEMBRANE: BINDING, DISASSEMBLY AND RE-DISTRIBUTION

The interaction of a self-assembled nanoparticle and a lipid membrane: Binding, disassembly and re-distribution

Here we report a detailed study of the interactions of nanoparticles, formed by the self-assembly of cholesterol-containing porphyrins, with lipid membranes.We show that the interaction is a two-step process: first, the docking and fusion, then, the redistribution of the building blocks of the self-assembled nanoparticles (SANs henceforth).Analysis

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Manipulating the Alpha Level Cannot Cure Significance Testing

We argue that making accept/reject decisions on scientific hypotheses, including a recent call for changing the canonical alpha level Air Duster Spray from p = 0.05 to p = 0.005, is deleterious for the finding of new discoveries and the progress of science.Given that blanket and variable alpha levels both are problematic, it is sensible to dispense

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